A comprehensive index of artificial intelligence and machine-learning research with AI-generated summaries, citation metrics, and direct links to papers and code.
Swen Hoelder, Paul A. Clarke, Paul Workman
This review outlines contemporary approaches to small molecule cancer drug discovery, emphasizing target validation, lead optimization, and biomarker-driven trials to reduce attrition and advance personalized medicine.
Tapas Kanungo, David M. Mount, Nathan S. Netanyahu, et al.
Presents a simple and efficient kd-tree-based filtering algorithm for Lloyd's k-means clustering with data-sensitive runtime analysis and empirical validation.
Paul C. D. Hawkins, A. Geoffrey Skillman, Gregory L. Warren, et al.
OMEGA is a systematic, knowledge-based conformer generator validated against high-quality PDB and CSD structures, showing strong performance in reproducing crystallographic conformations.